7-[2-(toluene-4-sulfonyloxy)ethyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester → 7-{2-[4-(5-Bromo-pyridin-2-ylmethoxy)-2-oxo-2H-pyridin-1-yl]-ethyl}-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][O:9][c:10]2[cH:11][c:12](=[O:16])[nH:13][cH:14][cH:15]2)[n:6][cH:7]1.[C:17]([CH3:18])([CH3:19])([CH3:20])[O:21][C:22](=[O:23])[N:24]1[CH2:25][c:26]2[cH:27][c:28]([CH2:34][CH2:35][O:36][S:37]([c:38]3[cH:39][cH:40][c:41]([CH3:42])[cH:43][cH:44]3)(=[O:45])=[O:46])[cH:29][cH:30][c:31]2[CH2:32][CH2:33]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][O:9][c:10]2[cH:11][c:12](=[O:16])[n:13]([CH2:35][CH2:34][c:28]3[cH:27][c:26]4[c:31]([cH:30][cH:29]3)[CH2:32][CH2:33][N:24]([C:22]([O:21][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:23])[CH2:25]4)[cH:14][cH:15]2)[n:6][cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-09868b1f238041e58b9bc21091110070
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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