2-Methyl-1-(piperidin-4-yl)propan-2-ol → 2-methyl-1-(1-((9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol

HRID 1239425Notes

Reaction equation

HRID 1239425 reaction equation
[Br:1][CH2:2][c:3]1[n:4]([CH3:28])[c:5]2[n:6][c:7](-[n:18]3[c:19]([CH3:27])[n:20][c:21]4[c:22]3[cH:23][cH:24][cH:25][cH:26]4)[n:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[c:10]2[n:11]1.[CH3:29][C:30]([CH2:31][CH:32]1[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]1)([CH3:38])[OH:39]>>[CH2:2]([c:3]1[n:4]([CH3:28])[c:5]2[n:6][c:7](-[n:18]3[c:19]([CH3:27])[n:20][c:21]4[c:22]3[cH:23][cH:24][cH:25][cH:26]4)[n:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[c:10]2[n:11]1)[N:35]1[CH2:34][CH2:33][CH:32]([CH2:31][C:30]([CH3:29])([CH3:38])[OH:39])[CH2:37][CH2:36]1

Participants

3

Reactant 2

HCID 184234282-Methyl-1-(piperidin-4-yl)propan-2-olHCID 596058124-(8-(bromomethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine

Product 1

HCID 596060902-methyl-1-(1-((9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol

Sources & evidence

ORD record
ord-155f258fdedd4d8f8a4dbd43b48d444a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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