2-Bromothiazole → Methyl 2-(7-chlorothieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazole-5-carboxylate

HRID 1239588Notes

Reaction equation

HRID 1239588 reaction equation
[Br:39][c:40]1[s:41][cH:42][cH:43][n:44]1.[Br:45][c:46]1[n:47]([CH3:55])[c:48]([C:51](=[O:52])[O:53][CH3:54])[cH:49][n:50]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9]([Sn:11]([CH2:12][CH2:13][CH2:14][CH3:15])([CH2:16][CH2:17][CH2:18][CH3:19])[CH2:20][CH2:21][CH2:22][CH3:23])[s:10]2.[Cl:24][c:25]1[cH:26][cH:27][n:28][c:29]2[cH:30][c:31](-[c:32]3[s:33][cH:34][cH:35][n:36]3)[s:37][c:38]12>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9](-[c:46]1[n:47]([CH3:55])[c:48]([C:51](=[O:52])[O:53][CH3:54])[cH:49][n:50]1)[s:10]2

Participants

5

Reactant 4

HCID 764302-BromothiazoleHCID 221436637-Chloro-2-(1,3-thiazol-2-yl)thieno[3,2-b]pyridineHCID 26343677Methyl 2-bromo-1-methyl-1H-imidazole-5-carboxylateHCID 575166587-Chloro-2-(tributylstannyl)thieno[3,2-b]pyridine

Product 1

HCID 59424560Methyl 2-(7-chlorothieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazole-5-carboxylate

Sources & evidence

ORD record
ord-e7bb54be3a124a55ac58a56e62b9a9f9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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