Potassium Cation → Cetirizine amide

HRID 1239876Notes

Reaction equation

HRID 1239876 reaction equation
[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:6][cH:7]1.[Cl:21][CH2:22][CH2:23][O:24][CH2:25][C:26](=[O:27])[NH2:28].[I-:36].[K+:35].[Na+:29].[Na+:30].[O-:31][C:32](=[O:33])[O-:34]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([N:9]2[CH2:10][CH2:11][N:12]([CH2:22][CH2:23][O:24][CH2:25][C:26](=[O:27])[NH2:28])[CH2:13][CH2:14]2)[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 813Potassium CationHCID 923Sodium ion2×HCID 1140TolueneHCID 9340NorchlorcyclizineHCID 19660Carbonate IonHCID 30165Iodide IonHCID 110189312-(2-Chloroethoxy)acetamide

Product 1

HCID 3068840Cetirizine amide

Sources & evidence

ORD record
ord-696d4310044145f2abb86d9a0fee73c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…