2-Ethylbenzimidazole → 2-(1-((5-(2-ethyl-1H-benzo[d]imidazol-1-yl)-7-morpholinothiazolo[4,5-d]pyrimidin-2-yl)methyl)piperidin-4-yl)propan-2-ol
Reaction equation
[C:39](=[O:40])([O-:41])[O-:42].[CH2:28]([CH3:29])[c:30]1[n:31][c:32]2[c:33]([nH:34]1)[cH:35][cH:36][cH:37][cH:38]2.[CH2:45]1[O:46][CH2:47][CH2:48][O:49][CH2:50]1.[Cl:1][c:2]1[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[n:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([C:18]([CH3:19])([CH3:20])[OH:21])[CH2:16][CH2:17]1)[s:10]2.[Cs+:43].[Cs+:44].[O:53]=[C:54]([CH:55]=[CH:56][c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1)[CH:63]=[CH:64][c:65]1[cH:66][cH:67][cH:68][cH:69][cH:70]1.[O:71]=[C:72]([CH:73]=[CH:74][c:75]1[cH:76][cH:77][cH:78][cH:79][cH:80]1)[CH:81]=[CH:82][c:83]1[cH:84][cH:85][cH:86][cH:87][cH:88]1.[O:89]=[C:90]([CH:91]=[CH:92][c:93]1[cH:94][cH:95][cH:96][cH:97][cH:98]1)[CH:99]=[CH:100][c:101]1[cH:102][cH:103][cH:104][cH:105][cH:106]1.[Pd:51].[Pd:52]>>[c:2]1(-[n:31]2[c:30]([CH2:28][CH3:29])[n:34][c:33]3[c:32]2[cH:38][cH:37][cH:36][cH:35]3)[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[n:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([C:18]([CH3:19])([CH3:20])[OH:21])[CH2:16][CH2:17]1)[s:10]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-20a6ca2d0c3d41858a4568fa642e82ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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