Hydroxide → 2-Amino-4-(4-amino-2-fluorophenoxy)pyridine

HRID 1240183Notes

Reaction equation

HRID 1240183 reaction equation
[H:24][H:25].[NH2:1][c:2]1[cH:3][c:4]([F:23])[c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][CH2:14][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)[n:10][cH:11][cH:12]2)[cH:21][cH:22]1.[OH-:26].[OH-:28].[Pd+2:27]>>[NH2:1][c:2]1[cH:3][c:4]([F:23])[c:5]([O:6][c:7]2[cH:8][c:9]([NH2:13])[n:10][cH:11][cH:12]2)[cH:21][cH:22]1

Participants

5

Reactant 4

HCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 598529014-(4-Amino-2-fluorophenoxy)-N-benzylpyridin-2-amineHCID 178418361HCID 178418361, compound

Product 1

HCID 231533352-Amino-4-(4-amino-2-fluorophenoxy)pyridine

Sources & evidence

ORD record
ord-6340d606ab2b4ea4b285ce14d089f898
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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