4-Methyl-5-(4-(methylsulfonyl)-3-(trifluoromethyl)phenyl)thiazol-2-amine → 4-{3-[5-(4-Methanesulfonyl-3-trifluoromethyl-phenyl)-4-methyl-thiazol-2-yl]-ureido}-butyric acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH2:6][CH2:7][NH:8][C:9](=[O:10])[NH:11][c:12]1[s:13][c:14](-[c:18]2[cH:19][c:20]([F:28])[c:21]([S:24](=[O:25])(=[O:26])[CH3:27])[cH:22][cH:23]2)[c:15]([CH3:17])[n:16]1)=[O:29].[CH3:30][S:31]([c:32]1[cH:33][cH:34][c:35](-[c:36]2[s:37][c:38]([NH2:39])[n:40][c:41]2[CH3:42])[cH:43][c:44]1[C:47]([F:48])([F:49])[F:50])(=[O:45])=[O:46]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH2:6][CH2:7][NH:8][C:9](=[O:10])[NH:11][c:12]1[s:13][c:14](-[c:18]2[cH:19][c:20]([C:47]([F:48])([F:49])[F:50])[c:21]([S:24](=[O:25])(=[O:26])[CH3:27])[cH:22][cH:23]2)[c:15]([CH3:17])[n:16]1)=[O:29]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f58a4cbe5d7d4773a33991ada36bc133
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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