2-amino-N-(2,4-dimethyl-3-(((2-methoxy-1-(pyridin-2-ylmethyl)-1H-benzo[d]imidazol-4-yl)oxy)methyl)phenyl)-N-methylacetamide → N-(2-((3-(((2-methoxy-1-(pyridin-2-ylmethyl)-1H-benzo[d]imidazol-4-yl)oxy)methyl)-2,4-dimethylphenyl)(methyl)amino)-2-oxoethyl)-3-(2-oxo-2,3-dihydrooxazolo[4,5-b]pyridin-6-yl)propanamide

HRID 1240314Notes

Reaction equation

HRID 1240314 reaction equation
[Cl:50][c:51]1[c:52]([CH2:53][O:54][c:55]2[c:56]3[n:57][c:58]([O:59][CH3:60])[n:61]([CH2:62][c:63]4[cH:64][cH:65][cH:66][cH:67][n:68]4)[c:69]3[cH:70][cH:71][cH:72]2)[c:73]([Cl:74])[cH:75][cH:76][c:77]1[N:78]([CH3:79])[C:80](=[O:81])[CH2:82][NH:83][C:84](=[O:85])[CH2:86][CH2:87][c:88]1[cH:89][cH:90][c:91]([C:92]([NH:93][CH2:94][CH2:95][O:96][CH3:97])=[O:98])[cH:99][cH:100]1.[NH2:1][CH2:2][C:3](=[O:4])[N:5]([CH3:6])[c:7]1[c:8]([CH3:34])[c:9]([CH2:14][O:15][c:16]2[cH:17][cH:18][cH:19][c:20]3[n:21]([CH2:27][c:28]4[n:29][cH:30][cH:31][cH:32][cH:33]4)[c:22]([O:25][CH3:26])[n:23][c:24]23)[c:10]([CH3:13])[cH:11][cH:12]1.[O:35]=[c:36]1[o:37][c:38]2[c:39]([n:40][cH:41][c:42]([CH2:44][CH2:45][C:46](=[O:47])[OH:48])[cH:43]2)[nH:49]1>>[NH:1]([CH2:2][C:3](=[O:4])[N:5]([CH3:6])[c:7]1[c:8]([CH3:34])[c:9]([CH2:14][O:15][c:16]2[cH:17][cH:18][cH:19][c:20]3[n:21]([CH2:27][c:28]4[n:29][cH:30][cH:31][cH:32][cH:33]4)[c:22]([O:25][CH3:26])[n:23][c:24]23)[c:10]([CH3:13])[cH:11][cH:12]1)[C:46]([CH2:45][CH2:44][c:42]1[cH:41][n:40][c:39]2[c:38]([o:37][c:36](=[O:35])[nH:49]2)[cH:43]1)=[O:47]

Participants

4

Reactant 3

HCID 667599582-amino-N-(2,4-dimethyl-3-(((2-methoxy-1-(pyridin-2-ylmethyl)-1H-benzo[d]imidazol-4-yl)oxy)methyl)phenyl)-N-methylacetamideHCID 667609784-(3-((2-((2,4-dichloro-3-(((2-methoxy-1-(pyridin-2-ylmethyl)-1H-benzo[d]imidazol-4-yl)oxy)methyl)phenyl)(methyl)amino)-2-oxoethyl)amino)-3-oxopropyl)-N-(2-methoxyethyl)benzamideHCID 667611473-(2-Oxo-2,3-dihydrooxazolo[4,5-b]pyridin-6-yl)propanoic acid

Product 1

HCID 66760605N-(2-((3-(((2-methoxy-1-(pyridin-2-ylmethyl)-1H-benzo[d]imidazol-4-yl)oxy)methyl)-2,4-dimethylphenyl)(methyl)amino)-2-oxoethyl)-3-(2-oxo-2,3-dihydrooxazolo[4,5-b]pyridin-6-yl)propanamide

Sources & evidence

ORD record
ord-390bd6e2b74f49bd98672f035c7726a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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