Acetone → Methyl 4-(benzyloxy)-2-hydroxybenzoate

HRID 1240892Notes

Reaction equation

HRID 1240892 reaction equation
[Br-:29].[C:21](=[O:22])([O-:23])[O-:24].[CH3:30][CH2:31][CH2:32][CH2:33][N+:34]([CH2:35][CH2:36][CH2:37][CH3:38])([CH2:39][CH2:40][CH2:41][CH3:42])[CH2:43][CH2:44][CH2:45][CH3:46].[CH3:47][C:48](=[O:49])[CH3:50].[Cl:13][CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1.[I-:28].[K+:25].[K+:26].[K+:27].[OH:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH3:7])[cH:8][cH:9][c:10]([OH:12])[cH:11]1>>[OH:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH3:7])[cH:8][cH:9][c:10]([O:12][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:11]1

Participants

9

Reactant 8

HCID 180AcetoneHCID 259Bromide ionHCID 813Potassium Cation3×HCID 7503Benzyl ChlorideHCID 16028TetrabutylammoniumHCID 16523Methyl 2,4-DihydroxybenzoateHCID 19660Carbonate IonHCID 30165Iodide Ion

Product 1

HCID 225489Methyl 4-(benzyloxy)-2-hydroxybenzoate

Sources & evidence

ORD record
ord-535152eac64547498d2f572a8c6231f7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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