Water → 4-(2-chloro-4-dimethylamino-5-fluoro-phenyl)-N2-(2-methoxy-1-methyl-ethyl)-pyridine-2,3-diamine

HRID 1240978Notes

Reaction equation

HRID 1240978 reaction equation
[Cl:1][c:2]1[c:3](-[c:12]2[c:13]([N+:24]([O-:25])=[O:26])[c:14]([NH:18][CH:19]([CH2:20][O:21][CH3:22])[CH3:23])[n:15][cH:16][cH:17]2)[cH:4][c:5]([F:11])[c:6]([N:8]([CH3:9])[CH3:10])[cH:7]1.[OH2:30].[Sn:27]([Cl:28])[Cl:29]>>[Cl:1][c:2]1[c:3](-[c:12]2[c:13]([NH2:24])[c:14]([NH:18][CH:19]([CH2:20][O:21][CH3:22])[CH3:23])[n:15][cH:16][cH:17]2)[cH:4][c:5]([F:11])[c:6]([N:8]([CH3:9])[CH3:10])[cH:7]1

Participants

4

Reactant 3

HCID 962WaterHCID 24479Stannous ChlorideHCID 22052192[4-(2-Chloro-4-dimethylamino-5-fluoro-phenyl)-3-nitro-pyridin-2-yl]-(2-methoxy-1-methyl-ethyl)-amine

Product 1

HCID 696581514-(2-chloro-4-dimethylamino-5-fluoro-phenyl)-N2-(2-methoxy-1-methyl-ethyl)-pyridine-2,3-diamine

Sources & evidence

ORD record
ord-be59c6eb127a41809bddec96ddd69439
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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