2-(Trifluoromethyl)benzenepropanoic acid → Ethyl 2-(7-bromo-1'-(3-(2-(trifluoromethyl)phenyl)propanoyl)-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetate
Reaction equation
[Br:16][c:17]1[cH:18][cH:19][cH:20][c:21]2[c:25]1[C:24]1([CH2:23][CH:22]2[CH2:31][C:32](=[O:33])[O:34][CH2:35][CH3:36])[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]1.[F:1][C:2]([c:3]1[c:4]([CH2:9][CH2:10][C:11](=[O:12])[OH:13])[cH:5][cH:6][cH:7][cH:8]1)([F:14])[F:15]>>[F:1][C:2]([c:3]1[c:4]([CH2:9][CH2:10][C:11](=[O:13])[N:28]2[CH2:27][CH2:26][C:24]3([CH2:23][CH:22]([CH2:31][C:32](=[O:33])[O:34][CH2:35][CH3:36])[c:21]4[cH:20][cH:19][cH:18][c:17]([Br:16])[c:25]43)[CH2:30][CH2:29]2)[cH:5][cH:6][cH:7][cH:8]1)([F:14])[F:15]Participants
3
Sources & evidence
- ORD record
- ord-0217ec3b9fce498baebedef516ea6588
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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