Potassium Cation → Methyl 2-(3,5-dichlorophenyl)isonicotinate

HRID 1241114Notes

Reaction equation

HRID 1241114 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:35][OH:36].[Cl:18][c:19]1[cH:20][c:21]([B:26]2[O:27][C:28]([CH3:29])([CH3:30])[C:31]([CH3:32])([CH3:33])[O:34]2)[cH:22][c:23]([Cl:25])[cH:24]1.[Cl:38][CH2:39][Cl:40].[Cl:7][c:8]1[cH:9][c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16][n:17]1.[K+:5].[K+:6].[OH2:37].[Pd:41]([Cl:42])[Cl:43]>>[c:8]1(-[c:21]2[cH:20][c:19]([Cl:18])[cH:24][c:23]([Cl:25])[cH:22]2)[cH:9][c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16][n:17]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 887MethanolHCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 24290Palladium ChlorideHCID 2736842Methyl 2-chloropyridine-4-carboxylateHCID 27582002-(3,5-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Product 1

HCID 66731520Methyl 2-(3,5-dichlorophenyl)isonicotinate

Sources & evidence

ORD record
ord-1c726de833854ee0a82c82ff138b6d9c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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