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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12412Generated: October 26, 2026

M-Cresol → t-butyl (1R)-2-(3-fluorophenoxy)-1-[(methylsulfanyl)methyl]ethylcarbamate

https://huagongshe.com/reaction/12412

Reaction equation

Participants

RoleNameHCIDCharge
ReactantM-CresolHCID 342—
Reactant3-FluorophenolHCID 9743—
Reactantt-butyl (1R)-2-hydroxy-1-[(methylsulfanyl)methyl]ethylcarbamateHCID 15192846—
Productt-butyl (1R)-2-(3-fluorophenoxy)-1-[(methylsulfanyl)methyl]ethylcarbamateHCID 86609357—

Reaction Steps

By the operation similar to that in Step 2 of Example 15 except that t-butyl (1R)-2-hydroxy-1-[(methylsulfanyl)methyl]ethylcarbamate (1 g) obtained in Step 1 was used as a starting material and m-cresol was changed to 3-fluorophenol, the title compound (300 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728005B2
Source datasetuspto-grants-2010_06
ORD IDord-b06412e6adab493bad4027094337a0c0
Source noteuspto-grants-2010_06