Oxygen → 4-Formylbenzoic acid

Participants

Reaction Steps

In a 500-ml titanium autoclave, 15.36 g (0.113 mol) of p-toluic acid, 1.16 g (5.65 mmol) of N-acetoxyphthalimide, 0.112 g (0.45 mmol) of cobalt(II) acetate tetrahydrate, 0.277 g (1.13 mmol) of manganese(II) acetate tetrahydrate and 107 g of acetic acid were placed, the resulting mixture was stirred at 150° C. in an atmosphere of a mixture of oxygen and nitrogen gases (1:1) [4 MPa (gauge pressure)] for 1 hour and thereby yielded terephthalic acid in a yield of 95.6% with a conversion from p-toluic acid of 97.4%. A small amount of 4-carboxybenzaldehyde was by-produced.

Provenance & Evidence