Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzoic Acid | HCID 243 | — |
| Reactant | Ethylbenzene | HCID 7500 | — |
| Reactant | 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl acetate | HCID 265566 | — |
| Catalyst | Cobalt(II) acetate tetrahydrate | HCID 61372 | — |
| Catalyst | Manganese acetate tetrahydrate | HCID 93021 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Acetophenone | HCID 7410 | 85% |
Reaction Steps
A mixture of 1.062 g (10 mmol) of ethylbenzene, 0.205 g (1 mmol) of N-acetoxyphthalimide, 0.025 g (0.1 mmol) of cobalt(II) acetate tetrahydrate, 0.025 g (0.1 mmol) of manganese(II) acetate tetrahydrate and 15 ml of acetic acid was stirred at 130° C. in an atmosphere of air [2 MPa (gauge pressure)] for 8 hours and thereby yielded benzoic acid in a yield of 85% (analyzed by gas chromatography) with a conversion from ethylbenzene of 96%. In this procedure, acetophenone was not produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07115541B2 |
|---|
| Source dataset | uspto-grants-2006_10 |
|---|
| ORD ID | ord-d9021c840955416daa5d73d9ce8b5d33 |
|---|
| Source note | uspto-grants-2006_10 |
|---|
