Dimethylformamide → HCID 86595784, compound

Participants

Reaction Steps

(S)-3-(1,3-benzodioxol-5-yl)-5-ethoxy-5-oxopentanoic acid (2.01, 7.2 mmol) was dissolved in methylene chloride (50 mL) at O° C. under argon. An excess of oxalyl chloride (3 mL) was added along with a drop of dimethylformamide (catalyst). The reaction mixture was stirred 24 hours and concentrated to a crude brown oil. Yield=2.23 g (>100%).

Provenance & Evidence