HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide → HCID 178508326, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide | HCID 11403986 | — |
| Reactant | HCID 178472140 | HCID 178472140 | — |
| Product | HCID 178508326 | HCID 178508326 | — |
Reaction Steps
2.43 g (9.02 mmol) of 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide from example I and ethyl cyano[(E)-phenyldiazenyl]acetate (1.96 g, 9.02 mmol) were heated under reflux for 12 h. After cooling to room temperature, the precipitate which had separated out was filtered off and washed several times with toluene. Flash chromatography (CH2Cl2/ethyl acetate 50:1→EA) afforded the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07115599B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-0a5970f0a4084a95be5c28136c5c0411 |
| Source note | uspto-grants-2006_10 |