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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1241544Generated: October 30, 2026

Hydrochloric Acid → HCID 21060604, compound

https://huagongshe.com/reaction/1241544

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantLithium HydroxideHCID 3939—
Reactant1H-indole-6-carboxylic acidHCID 595230—
ReactantHCID 21060522HCID 21060522—
ProductHCID 21060604HCID 21060604—

Reaction Steps

Prepared from 1-[(γ-methyl)-D-glutamyl]-4-(1-methylpiperidin-4-yl)piperidine dihydrochloride and indole-6-carboxylic acid using methods substantially equivalent to General Coupling Method 1. Ester deprotection with 2 eq LiOH and final purification and HCl salt formation via prep HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115609B2
Source datasetuspto-grants-2006_10
ORD IDord-ccf0d46f2d214a45b4e6630091dc3971
Source noteuspto-grants-2006_10