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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1241597Generated: October 30, 2026

3,4,5-Trimethoxyaniline → N2-(3,4,5-Trimethoxyphenyl)-N4-(5-phenylisoxazol-3-yl)-2,4-pyrimidinediamine

https://huagongshe.com/reaction/1241597

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4,5-TrimethoxyanilineHCID 32285—
Reactant2-chloro-N4-(5-phenylisoxazol-3-yl)-4-pyrimidineamineHCID 21936456—
ProductN2-(3,4,5-Trimethoxyphenyl)-N4-(5-phenylisoxazol-3-yl)-2,4-pyrimidinediamineHCID 21060794—

Reaction Steps

The title compound was prepared by the method described in Example 1 using 2-chloro-N4-(5-phenylisoxazol-3-yl)-4-pyrimidineamine and 3,4,5-trimethoxyaniline. MS (MH+)=420.4, Calc'd for C22H21N5O4— 419.44.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115617B2
Source datasetuspto-grants-2006_10
ORD IDord-9f7259e4eaf046b587042c1ad3638129
Source noteuspto-grants-2006_10