4,5-Dimethoxy-2-methylaniline → N2-(2-methyl-4,5-dimethoxyphenyl)-N4-(5-phenylisoxazol-3-yl)-2,4-pyrimidinediamine

HRID 1241598Notes

Reaction equation

HRID 1241598 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[O:11][N:10]=2)[CH:5]=[CH:4][N:3]=1.[CH3:20][C:21]1[CH:27]=[C:26]([O:28][CH3:29])[C:25]([O:30][CH3:31])=[CH:24][C:22]=1[NH2:23]>>[CH3:20][C:21]1[CH:27]=[C:26]([O:28][CH3:29])[C:25]([O:30][CH3:31])=[CH:24][C:22]=1[NH:23][C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[O:11][N:10]=2)[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 2665854,5-Dimethoxy-2-methylanilineHCID 219364562-chloro-N4-(5-phenylisoxazol-3-yl)-4-pyrimidineamine

Product 1

HCID 21060791N2-(2-methyl-4,5-dimethoxyphenyl)-N4-(5-phenylisoxazol-3-yl)-2,4-pyrimidinediamine

Procedure

The title compound was prepared by the method described in Example 1 using 2-chloro-N4-(5-phenylisoxazol-3-yl)-4-pyrimidineamine and 2-methyl-4,5-dimethoxyaniline.

Sources & evidence

ORD record
ord-e9d11176a4e84e96afae5a34b4af36b6
Source dataset
uspto-grants-2006_10
Patent number
US07115617B2

Reaction notes

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