3,4,5-Trimethoxyaniline → HCID 21060786, compound

HRID 1241601Notes

Reaction equation

HRID 1241601 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]2[O:13][N:12]=[C:11]([CH:14]3[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]3)[CH:10]=2)[CH:5]=[CH:4][N:3]=1.[CH3:20][O:21][C:22]1[CH:23]=[C:24]([CH:26]=[C:27]([O:31][CH3:32])[C:28]=1[O:29][CH3:30])[NH2:25]>>[CH3:32][O:31][C:27]1[CH:26]=[C:24]([NH:25][C:2]2[N:7]=[C:6]([NH:8][C:9]3[O:13][N:12]=[C:11]([CH:14]4[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]4)[CH:10]=3)[CH:5]=[CH:4][N:3]=2)[CH:23]=[C:22]([O:21][CH3:20])[C:28]=1[O:29][CH3:30]

Participants

3

Reactant 2

HCID 322853,4,5-TrimethoxyanilineHCID 86211338HCID 86211338, compound

Product 1

HCID 21060786HCID 21060786, compound

Procedure

The title compound was prepared by the method described in Example 1 using 2-chloro-N4-(3-cyclohexylisoxazol-5-yl)-4-pyrimidineamine (Step C) and 3,4,5-trimethoxyaniline. MS (MH+)=426.5; Calc'd for C22H27N5O4— 425.49.

Sources & evidence

ORD record
ord-47c85efef47f4b1e8bf94599993abb28
Source dataset
uspto-grants-2006_10
Patent number
US07115617B2

Reaction notes

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