反应详情

温度

0 °C

To the compound obtained in Step 2 were added 30% hydrobromide/acetic acid (1 ml) and dichloromethane (2 ml), and the mixture was stirred at 0° C. for 2 hrs. The mixture was diluted with dichloromethane, and washed with saturated aqueous sodium hydrogen carbonate. The organic layer was dried over anhydrous sodium sulfate and the solvent was evaporated to give the title compound as a crude product.

1. washwashed with saturated aqueous sodium hydrogen carbonate
2. dry with materialThe organic layer was dried over anhydrous sodium sulfate
3. customthe solvent was evaporated