HCID 9843930, compound → HCID 21936636, compound

Participants

Reaction Steps

The procedure of Example 7(2) was repeated using 1-(3-nitrophenyl)-3-[3-methyl-3-(pyridin-4-yl)propyl]-1,8-naphthyridin-2(1H)-one (1.19 g, 2.97 mmol; prepared in Example 11) and 10% palladium on carbon (200 mg) to obtain 1-(3-aminophenyl)-3-[3-methyl-3-(pyridin-4-yl)propyl]-1,8-naphthyridin-2(1H)-one (757 mg, 89%). The product was purified through flash column chromatography (mp 83–91° C.).

Provenance & Evidence