HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tin tetrachloride → HCID 21936647, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tin tetrachloride | HCID 24287 | — |
| Reactant | HCID 21936644 | HCID 21936644 | — |
| Product | HCID 21936647 | HCID 21936647 | 65.1% |
Reaction Steps
The procedure of Example 19 was repeated using 1-(3-nitrophenyl)-3-[3-hydroxy-3-(pyridin-4-yl)propyl]-1,8-naphthyridin-2(1H)-one (400 mg, 0.99 mmol; prepared in Example 20) and tin chloride.2H2O (2 g, 5-fold weights) while ice-cooling to obtain 1-(3-aminophenyl)-3-[3-hydroxy-3-(pyridin-4-yl)propyl]-1,8-naphthyridin-2(1H)-one (240 mg, 65%; mp 209–211° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07115623B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-196b598f6df4456cbf4779d28e32083b |
| Source note | uspto-grants-2006_10 |