Benzothiazolium, 3-methyl-2-(methylthio)-, 4-methylbenzenesulfonate (1:1) → 2-(3-acetylphenylimino)-5-(3-methyl-3H-benzothiazol-2-ylidene)-3-pyridin-3-ylmethylthiazolidin-4-one
Reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([N:10]=[C:11]2[N:15]([CH2:16][C:17]3[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=3)[C:14](=[O:23])[CH2:13][S:12]2)[CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2].C1(C)C=CC(S([O-])(=O)=O)=CC=1.[CH3:35][N+:36]1[C:40]2[CH:41]=[CH:42][CH:43]=[CH:44][C:39]=2[S:38][C:37]=1SC>>[C:1]([C:4]1[CH:5]=[C:6]([N:10]=[C:11]2[N:15]([CH2:16][C:17]3[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=3)[C:14](=[O:23])[C:13](=[C:37]3[N:36]([CH3:35])[C:40]4[CH:41]=[CH:42][CH:43]=[CH:44][C:39]=4[S:38]3)[S:12]2)[CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2]Participants
3
Procedure
The title compound was prepared from intermediate 2-(3-acetylphenylimino)-3-pyridin-3-ylmethylthiazolidin-4-one and 3-methyl-2-(methylthio)benzothiazol-3-ium p-toluenesulfonate as described in Example 45. 1H-NMR (CDCl3): δ 8.87 (1H, d), 8.56 (1H, dd), 7.93 (1H, m), 7.74 (1H, m), 7.60 (1H, m), 7.53 (1H, d), 7.46 (1H, m), 7.27–7.38 (2H, m), 7.17–7.23 (2H, m), 7.05 (1H, d), 5.18 (2H, s), 3.74 (3H, s), 2.62 (3H, s); MS(ESI): 473 (MH+).
Sources & evidence
- ORD record
- ord-219ad8cb787742638288eb08238d0f43
- Source dataset
- uspto-grants-2006_10
- Patent number
- US07115640B2
Reaction notes
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