Ethylamine → 3'-Ethylamino-4'-nitroacetanilide

HRID 1241973Notes

Reaction equation

HRID 1241973 reaction equation
F[C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:5][C:6](=[O:8])[CH3:7].[CH2:15]([NH2:17])[CH3:16]>>[CH2:15]([NH:17][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:5][C:6](=[O:8])[CH3:7])[CH3:16]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 2755770N-(3-Fluoro-4-nitrophenyl)acetamide

Product 1

HCID 219374493'-Ethylamino-4'-nitroacetanilide

Procedure

In a manner similar to Example 31, the title compound was prepared from 3′-fluoro-4′-nitroacetanilide and ethylamine. 1H-NMR (CDCl3): δ 8.17 (1H, brs), 8.13 (1H, d), 7.57 (1H, br d), 7.33 (1H, brs), 6.38 (1H, dd), 3.36 (2H, m), 2.22 (3H, s), 1.37 (3H, t).

Sources & evidence

ORD record
ord-1db8062a371f4377bfe396ac57140df1
Source dataset
uspto-grants-2006_10
Patent number
US07115640B2

Reaction notes

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