HCID 21937402, compound → HCID 73855083, compound

HRID 1241978Notes

Reaction equation

HRID 1241978 reaction equation
[CH3:1][N:2]([CH3:20])[CH2:3][CH2:4][NH:5][C:6](=[O:19])[C:7]1[CH:12]=[CH:11][C:10]([NH:13][CH2:14][CH3:15])=[C:9]([N+:16]([O-])=O)[CH:8]=1.C1(C)C=CC(S([O-])(=O)=O)=CC=1.[CH2:32]([N:39]1[C:43](=[O:44])[C:42](=[C:45]2[N:49]([CH3:50])[C:48]3[CH:51]=[CH:52][CH:53]=[CH:54][C:47]=3[S:46]2)[S:41][CH2+:40]1SC)[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1>>[CH2:32]([N:39]1[C:43](=[O:44])[C:42](=[C:45]2[N:49]([CH3:50])[C:48]3[CH:51]=[CH:52][CH:53]=[CH:54][C:47]=3[S:46]2)[S:41][C:40]1=[N:16][C:9]1[CH:8]=[C:7]([CH:12]=[CH:11][C:10]=1[NH:13][CH2:14][CH3:15])[C:6]([NH:5][CH2:4][CH2:3][N:2]([CH3:20])[CH3:1])=[O:19])[C:33]1[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=1

Participants

2

Reactant 1

HCID 21937402HCID 21937402, compound

Product 1

HCID 73855083HCID 73855083, compound

Procedure

In a manner similar to Example 30, intermediate N-(2-dimethylaminoethyl)-4-ethylamino-3-nitrobenzamide was hydrogenated and then condensed with 3-benzyl-5-(3-methyl-3H-benzothiazol-2-ylidene)-2-methylthio-4-oxo-2-thiazolium p-toluenesulfonate to afford the title compound.

Sources & evidence

ORD record
ord-934b90dddde449798140e0eb553670aa
Source dataset
uspto-grants-2006_10
Patent number
US07115640B2

Reaction notes

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