HCID 21937615, compound → HCID 73854978, compound

HRID 1242004Notes

Reaction equation

HRID 1242004 reaction equation
[CH3:1][N:2]([CH3:19])[CH2:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][CH2:14][CH3:15])=[C:9]([N+:16]([O-])=O)[CH:8]=1)=[O:5].C1(C)C=CC(S([O-])(=O)=O)=CC=1.[CH2:31]([N:38]1[C:42](=[O:43])[C:41](=[C:44]2[N:48]([CH3:49])[C:47]3[CH:50]=[C:51]([O:54][CH2:55][CH2:56][Cl:57])[CH:52]=[CH:53][C:46]=3[S:45]2)[S:40][CH2+:39]1SC)[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH2:31]([N:38]1[C:42](=[O:43])[C:41](=[C:44]2[N:48]([CH3:49])[C:47]3[CH:50]=[C:51]([O:54][CH2:55][CH2:56][Cl:57])[CH:52]=[CH:53][C:46]=3[S:45]2)[S:40][C:39]1=[N:16][C:9]1[CH:8]=[C:7]([NH:6][C:4](=[O:5])[CH2:3][N:2]([CH3:19])[CH3:1])[CH:12]=[CH:11][C:10]=1[NH:13][CH2:14][CH3:15])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1

Participants

2

Reactant 1

HCID 21937615HCID 21937615, compound

Product 1

HCID 73854978HCID 73854978, compound

Procedure

In a manner similar to Example 30, intermediate 2-dimethylamino-4′-ethylamino-3′-nitroacetanilide was hydrogenated and then condensed with 3-benzyl-5-[5-(2-chloroethoxy)-3-methylbenzothiazol-2-ylidene]-2-methylthio-4-oxo-2-thiazolium p-toluenesulfonate to afford the title compound. MS(ESI): 651 (MH+).

Sources & evidence

ORD record
ord-e8aa1699d496489597a5b4bd9faaeaad
Source dataset
uspto-grants-2006_10
Patent number
US07115640B2

Reaction notes

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