HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl p-toluenesulfonate → 2-(5-Acetyl-2-ethylaminophenylimino)-5-[5-(2-chloroethoxy)-3-methyl-3H-benzothiazol-2-ylidene]-3-furan-2-ylmethylthiazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl p-toluenesulfonate | HCID 6645 | — |
| Reactant | 5-(2-Chloroethoxy)-2-methylthio-benzothiazole | HCID 21937487 | — |
| Reactant | 2-(5-Acetyl-2-ethylaminophenylimino)-3-furan-2-ylmethyl-thiazolidin-4-one | HCID 21937511 | — |
| Product | 2-(5-Acetyl-2-ethylaminophenylimino)-5-[5-(2-chloroethoxy)-3-methyl-3H-benzothiazol-2-ylidene]-3-furan-2-ylmethylthiazolidin-4-one | HCID 73855140 | — |
Reaction Steps
In a manner similar to Example 45, intermediate 5-(2-chloroethoxy)-2-(methylthio)benzothiazole was alkylated with methyl p-toluenesulfonate and then condensed with the above 2-(5-acetyl-2-ethylaminophenylimino)-3-furan-2-ylmethyl-thiazolidin-4-one. MS(ESI): 583 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07115640B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-c3b668bf83bd423da5a3f7f1e827297d |
| Source note | uspto-grants-2006_10 |