Dichloromethane → 5-(Benzyloxy)pent-3-en-2-one

Participants

Reaction Steps

Benzyloxyacetaldehyde (0.90 g; 6.0 mmol) and dimethyl(2-oxomethyl)phosphonate (1.0 g; 6.0 mmol) were dissolved in a mixture of tetrahydrofuran (25 ml) and water (20 ml). 1N Aqueous potassium hydroxide (6 ml) was added and the mixture was stirred for 30 min. Dichloromethane (50 ml) was added and the organic phase was separated, dried (MgSO4) and evaporated in vacuo leaving 5-benzyloxypent-3-en-2-one.

Provenance & Evidence