N-Acetylsulfanilyl chloride → HCID 10146280, compound

HRID 1242189Notes

Reaction equation

HRID 1242189 reaction equation
[CH:1]([O:4][C:5](=[O:34])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[C:13]([NH2:33])=[CH:14][C:15]2[N:19]=[C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[N:17]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[C:16]=2[CH:32]=1)([CH3:3])[CH3:2].[C:35]([NH:38][C:39]1[CH:44]=[CH:43][C:42]([S:45](Cl)(=[O:47])=[O:46])=[CH:41][CH:40]=1)(=[O:37])[CH3:36]>>[CH:1]([O:4][C:5](=[O:34])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[C:13]([NH:33][S:45]([C:42]2[CH:41]=[CH:40][C:39]([NH:38][C:35](=[O:37])[CH3:36])=[CH:44][CH:43]=2)(=[O:47])=[O:46])=[CH:14][C:15]2[N:19]=[C:18]([C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)[N:17]([C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)[C:16]=2[CH:32]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 8481N-Acetylsulfanilyl chlorideHCID 673640426-[(5-Amino-1,2-diphenyl-1H-benzimidazol-6-yl)oxy]hexanoic acid isopropyl ester

Product 1

HCID 10146280HCID 10146280, compound

Procedure

6-[(5-Amino-1,2-diphenyl-1H-benzimidazol-6-yl)oxy]hexanoic acid isopropyl ester was reacted according to general operating instructions 13 with 4-(acetylamino)benzenesulfonic acid chloride.

Sources & evidence

ORD record
ord-382cb1242bf4423eba82cbb5522bf175
Source dataset
uspto-grants-2006_10
Patent number
US07115645B2

Reaction notes

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