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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1242213Generated: October 25, 2026

4-Chlorobenzenesulfonyl chloride → 6-[[5-[[(4-Chlorophenyl)sulfonyl]amino]-1-(4-methoxyphenyl)-2-phenyl-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl ester

https://huagongshe.com/reaction/1242213

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzenesulfonyl chlorideHCID 7398—
Reactant6-[(5-Amino-1-(4-methoxyphenyl)-2-phenyl-1H-benzimidazol-6-yl)oxy]hexanoic acid methyl esterHCID 67364071—
Product6-[[5-[[(4-Chlorophenyl)sulfonyl]amino]-1-(4-methoxyphenyl)-2-phenyl-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl esterHCID 10282837—

Reaction Steps

6-[(5-Amino-1-(4-methoxyphenyl)-2-phenyl-1H-benzimidazol-6-yl)oxy]hexanoic acid methyl ester was reacted with 4-chlorobenzenesulfonic acid chloride according to general operating instructions 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115645B2
Source datasetuspto-grants-2006_10
ORD IDord-596fd8ef5c1641f389ba749d4af6508e
Source noteuspto-grants-2006_10