Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Methyl 6-Bromohexanoate | HCID 4170292 | — |
| Reactant | HCID 21938095 | HCID 21938095 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67366436 | HCID 67366436 | — |
Reaction Steps
150 mg of 4-(trifluoromethyl)-N-(1,2-diphenyl-1H-benzimidazol-5-yl)benzenesulfonamide was suspended in 0.5 ml of N,N-dimethylformamide, mixed with 11 mg of sodium hydride and stirred for 30 minutes at 20° C. 88 mg of 6-bromohexanoic acid methyl ester was added, it was allowed to stir for 15 hours, mixed with water, extracted three times with ethyl acetate, the extracts were dried on sodium sulfate, concentrated by evaporation in a vacuum, and the residue was digested with diisopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07115645B2 |
|---|
| Source dataset | uspto-grants-2006_10 |
|---|
| ORD ID | ord-e785a6453fb140c08d0cc39227157427 |
|---|
| Source note | uspto-grants-2006_10 |
|---|
