HRID1242349

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21935769

未命名化合物

结构：CCCC(Cl)c1ccc(-c2cccc(C(F)(F)F)c2)nc1C

HCID21935942

未命名化合物

结构：CCCC(Oc1ccc(OC(C)(C)C(=O)OCC)c(C)c1)c1ccc(-c2cccc(C(F)(F)F)c2)nc1C

HCID67072149

未命名化合物

PRODUCTS

生成物

结构：CCCC(Oc1ccc(OC(C)(C)C(=O)O)c(C)c1)c1ccc(-c2cccc(C(F)(F)F)c2)nc1C

HCID21935635

未命名化合物

PROCEDURE

实验过程

A] The title compound was prepared in analogy to example 8, via [rac]-2-methyl-2-(2-methyl-4-{1-[2-methyl-6-(3-trifluoromethyl-phenyl)-pyridin-3-yl]-butoxy}-phenoxy)-propionic acid ethyl ester, but using instep A] [rac]-3-(1-chloro-butyl)-2-methyl-6-(3-trifluoromethyl-phenyl)-pyridine (example 4B]) instead of 3-chloromethyl-2-methyl-6-(3-trifluoromethyl-phenyl)-pyridine, as white foam.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3002cee936f64f7b8e271a98f869b9da
来源数据集: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07115611B2
来源说明: uspto-grants-2006_10

反应 SMILES

C([O:3][C:4](=[O:38])[C:5]([CH3:37])([O:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH:15]([C:19]2[C:20]([CH3:35])=[N:21][C:22]([C:25]3[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:34])([F:33])[F:32])[CH:26]=3)=[CH:23][CH:24]=2)[CH2:16][CH2:17][CH3:18])=[CH:10][C:9]=1[CH3:36])[CH3:6])C.ClC(C1C(C)=NC(C2C=CC=C(C(F)(F)F)C=2)=CC=1)CCC.ClCC1C(C)=NC(C2C=CC=C(C(F)(F)F)C=2)=CC=1>>[CH3:6][C:5]([O:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH:15]([C:19]2[C:20]([CH3:35])=[N:21][C:22]([C:25]3[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:33])([F:32])[F:34])[CH:26]=3)=[CH:23][CH:24]=2)[CH2:16][CH2:17][CH3:18])=[CH:10][C:9]=1[CH3:36])([CH3:37])[C:4]([OH:38])=[O:3]