Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 67072313, compound

HRID 1242408Notes

Reaction equation

HRID 1242408 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([OH:14])[CH:7]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:9]=1)([O-:3])=[O:2].Br[C:16]([CH3:23])([CH3:22])[C:17]([O:19][CH2:20][CH3:21])=[O:18]>>[CH2:20]([O:19][C:17](=[O:18])[C:16]([CH3:23])([O:14][C:6]1[CH:7]=[C:8]([C:10]([F:11])([F:12])[F:13])[CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)[CH3:22])[CH3:21]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 27562513-Hydroxy-5-nitrobenzotrifluoride

Product 1

HCID 67072313HCID 67072313, compound

Procedure

In analogy to the procedure described in example 52A], 3-nitro-5-trifluoromethyl-phenol [PCT Int. Appl. (1994), WO 94/20467A1] was reacted with ethyl bromoisobutyrate to yield the title compound as yellow oil.

Sources & evidence

ORD record
ord-c73da48170ef4ecf8110de115ce6a504
Source dataset
uspto-grants-2006_10
Patent number
US07115611B2

Reaction notes

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