Ethyl 2-(4-hydroxy-2-methylphenoxy)-2-methylpropanoate → HCID 67072152, compound

HRID 1242514Notes

Reaction equation

HRID 1242514 reaction equation
[CH2:1]([O:3][C:4](=[O:17])[C:5]([O:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][C:10]=1[CH3:16])([CH3:7])[CH3:6])[CH3:2].Cl[CH2:19][C:20]1[C:21]([CH2:38][O:39][CH3:40])=[N:22][C:23]([C:27]2[CH:32]=[CH:31][C:30]([O:33][C:34]([F:37])([F:36])[F:35])=[CH:29][CH:28]=2)=[N:24][C:25]=1[CH3:26]>>[CH2:1]([O:3][C:4](=[O:17])[C:5]([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:19][C:20]2[C:21]([CH2:38][O:39][CH3:40])=[N:22][C:23]([C:27]3[CH:28]=[CH:29][C:30]([O:33][C:34]([F:37])([F:35])[F:36])=[CH:31][CH:32]=3)=[N:24][C:25]=2[CH3:26])=[CH:11][C:10]=1[CH3:16])([CH3:6])[CH3:7])[CH3:2]

Participants

3

Reactant 2

HCID 16756990Ethyl 2-(4-hydroxy-2-methylphenoxy)-2-methylpropanoateHCID 21935686HCID 21935686, compound

Product 1

HCID 67072152HCID 67072152, compound

Procedure

In analogy to the procedure described in example 113A], 2-(4-hydroxy-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester (described in WO 02/092590) was reacted with 5-chloromethyl-4-methoxymethyl-6-methyl-2-(4-trifluoromethoxy-phenyl)-pyrimidine (example 149D]) to give the title compound as light yellow viscous oil.

Sources & evidence

ORD record
ord-240942c322ce47e2bfa33415a0002ad7
Source dataset
uspto-grants-2006_10
Patent number
US07115611B2

Reaction notes

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