Thionyl Chloride → HCID 21935686, compound

HRID 1242515Notes

Reaction equation

HRID 1242515 reaction equation
[CH3:1][O:2][CH2:3][C:4]1[C:9]([CH2:10]O)=[C:8]([CH3:12])[N:7]=[C:6]([C:13]2[CH:18]=[CH:17][C:16]([O:19][C:20]([F:23])([F:22])[F:21])=[CH:15][CH:14]=2)[N:5]=1.S(Cl)([Cl:26])=O>>[Cl:26][CH2:10][C:9]1[C:4]([CH2:3][O:2][CH3:1])=[N:5][C:6]([C:13]2[CH:18]=[CH:17][C:16]([O:19][C:20]([F:23])([F:22])[F:21])=[CH:15][CH:14]=2)=[N:7][C:8]=1[CH3:12]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 21935712HCID 21935712, compound

Product 1

HCID 21935686HCID 21935686, compound

Procedure

In analogy to the procedure described in example 113H], [4-methoxymethyl-6-methyl-2-(4-trifluoromethoxy-phenyl)-pyrimidin-5-yl]-methanol and thionylchloride gave the title compound as a brown oil.

Sources & evidence

ORD record
ord-5bcd74a2759744ba88d1c994e9189053
Source dataset
uspto-grants-2006_10
Patent number
US07115611B2

Reaction notes

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