Thionyl Chloride → HCID 21935711, compound

HRID 1242536Notes

Reaction equation

HRID 1242536 reaction equation
[CH3:1][O:2][CH2:3][C:4]1[C:9]([CH2:10]O)=[CH:8][N:7]=[C:6]([C:12]2[CH:17]=[CH:16][C:15]([O:18][C:19]([F:22])([F:21])[F:20])=[CH:14][CH:13]=2)[N:5]=1.S(Cl)([Cl:25])=O>>[Cl:25][CH2:10][C:9]1[C:4]([CH2:3][O:2][CH3:1])=[N:5][C:6]([C:12]2[CH:17]=[CH:16][C:15]([O:18][C:19]([F:22])([F:21])[F:20])=[CH:14][CH:13]=2)=[N:7][CH:8]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 21935845HCID 21935845, compound

Product 1

HCID 21935711HCID 21935711, compound

Procedure

In analogy to the procedure described in example 113H], [4-methoxymethyl-2-(4-trifluoromethoxy-phenyl)-pyrimidin-5-yl]-methanol and thionylchloride gave the title compound as a brown oil.

Sources & evidence

ORD record
ord-fdff43e19d8e44f18ef9aaaaabaa9cca
Source dataset
uspto-grants-2006_10
Patent number
US07115611B2

Reaction notes

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