HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3,5-DIOXOPIPERAZIN-1-YL)ACETIC ACID → HCID 58714511, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3,5-DIOXOPIPERAZIN-1-YL)ACETIC ACID | HCID 4439662 | — |
| Reactant | (2S,4EZ)-1-([1,1'-biphenyl]-4-ylcarbonyl)-N'-hydroxy-4-(methoxyimino)-2-pyrrolidinecarboximidamide | HCID 90995821 | — |
| Product | HCID 58714511 | HCID 58714511 | 55% |
Reaction Steps
Following the general method as outlined in Example 15, starting from (2S,4EZ)-1-([1,1′-biphenyl]-4-ylcarbonyl)-N′-hydroxy-4-(methoxyimino)-2-pyrrolidinecarboximidamide (Intermediate 8) and (3,5-dioxo-1-piperazinyl)acetic acid, the title compound was obtained in 55% yield (99.0% purity by HPLC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07115639B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-9c9f7f08c872434bbbe94e2b95989d0a |
| Source note | uspto-grants-2006_10 |