(3S)-1-((tert-butoxy)carbonyl)piperidine-3-carboxylic acid → HCID 58714557, compound

Participants

Reaction Steps

Following the general method as outlined in Example 15, starting from (2S,4EZ)-1-([1,1′-biphenyl]-4-ylcarbonyl)-N′-hydroxy-4-(methoxyimino)-2-pyrrolidinecarboximidamide (Intermediate 8) and (3S)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylic acid, the title compound, tert-butyl (3S)-3-{3-[(2S,4EZ)-1-([1,1′-biphenyl]-4-ylcarbonyl)-4-(methoxyimino)pyrrolidinyl]-1,2,4-oxadiazol-5-yl}-1-piperidinecarboxylate, was obtained in 85% yield (97.20% purity by HPLC).

Provenance & Evidence