HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylbenzoyl chloride → HCID 58714530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylbenzoyl chloride | HCID 84151 | — |
| Reactant | 4-Fluoro-n-hydroxybenzimidamide | HCID 593000 | — |
| Reactant | (2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid | HCID 58714586 | — |
| Product | HCID 58714530 | HCID 58714530 | — |
Reaction Steps
Following the general method as outlined in Example 59, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidine-carboxylic acid (Intermediate 2), [1,1′-biphenyl]-4-carbonyl chloride, and 4-fluoro-N′-hydroxybenzenecarboximidamide, the title compound was obtained in 79% purity by HPLC. MS(ESI+): m/z=457.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07115639B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-335f1176774946d1aa4e11fa990cf53c |
| Source note | uspto-grants-2006_10 |