Dichloromethane → tert-butyl 4-(1-methyl-1H-imidazol-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate

HRID 124263Notes

Reaction equation

HRID 124263 reaction equation
[CH3:21][S:22](=[O:23])(=[O:24])[Cl:25].[Cl:26][CH2:27][Cl:28].[OH:1][C:2]1([c:15]2[n:16]([CH3:20])[cH:17][cH:18][n:19]2)[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1>>[C:2]1([c:15]2[n:16]([CH3:20])[cH:17][cH:18][n:19]2)=[CH:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 31297Methanesulfonyl chlorideHCID 68570244tert-butyl 4-hydroxy-4-(1-methyl-1H-imidazol-2-yl)piperidine-1-carboxylate

Product 1

HCID 68598207tert-butyl 4-(1-methyl-1H-imidazol-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-98b87cc20f1d4148bd0c04b7ba9cc636
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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