HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)phenyl isocyanate → N-(1-Benzyl-pyrrolidin-3-(S)-yl)-3,3-dimethyl-2-(S)-[3-(3-trifluoromethyl-phenyl)-ureido]-butyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)phenyl isocyanate | HCID 9483 | — |
| Reactant | 2-(S)-Amino-N-(1-benzyl-pyrrolidin-3-(S)-yl)-3,3-dimethyl-butyramide | HCID 21062337 | — |
| Product | N-(1-Benzyl-pyrrolidin-3-(S)-yl)-3,3-dimethyl-2-(S)-[3-(3-trifluoromethyl-phenyl)-ureido]-butyramide | HCID 10299251 | — |
Reaction Steps
Compound 3b was prepared from 3-(trifluoromethyl)phenyl isocyanate and compound 2b, using the method described in Example 9. MS (EI)=476 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07115664B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-0b673039233a473584123ce2ae54d74d |
| Source note | uspto-grants-2006_10 |