1,4-Difluoro-2-isocyanatobenzene → N-(1-Benzyl-pyrrolidin-3-(S)-yl)-2-(S)-[3-(2,5-difluoro-phenyl)-ureido]-3,3-dimethyl-butyramide

Participants

Role	Name	HCID	Charge
Reactant	1,4-Difluoro-2-isocyanatobenzene	HCID 2733266	—
Reactant	2-(S)-Amino-N-(1-benzyl-pyrrolidin-3-(S)-yl)-3,3-dimethyl-butyramide	HCID 21062337	—
Product	N-(1-Benzyl-pyrrolidin-3-(S)-yl)-2-(S)-[3-(2,5-difluoro-phenyl)-ureido]-3,3-dimethyl-butyramide	HCID 10138400	—

Compound 3c was prepared from 2,5-difluorophenyl isocyanate and compound 2b, using the method described in Example 9. MS (EI)=444 (M+).