4-Hydroxy-4-m-tolyl-cyclohexanone → N-{[1-(4-Hydroxy-4-m-tolyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide
Reaction equation
[NH:16]1[CH2:17][CH:18]([NH:20][C:21](=[O:22])[CH2:23][NH:24][C:25]([c:26]2[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]2)=[O:36])[CH2:19]1.[OH:1][C:2]1([c:9]2[cH:10][c:11]([CH3:15])[cH:12][cH:13][cH:14]2)[CH2:3][CH2:4][C:5](=[O:8])[CH2:6][CH2:7]1>>[OH:1][C:2]1([c:9]2[cH:10][c:11]([CH3:15])[cH:12][cH:13][cH:14]2)[CH2:3][CH2:4][CH:5]([N:16]2[CH2:17][CH:18]([NH:20][C:21](=[O:22])[CH2:23][NH:24][C:25]([c:26]3[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]3)=[O:36])[CH2:19]2)[CH2:6][CH2:7]1Participants
3
Sources & evidence
- ORD record
- ord-369b55fd4dcf44fea6b53411396c4e09
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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