HCID 21939720, compound → HCID 21940024, compound

Participants

Reaction Steps

A methanol solution (5 ml) of N-[6-[2-(dimethylamino)ethyl] 7,8-dihydro-2-naphthalenyl][1,1′-biphenyl]-4-carboxamide (20 mg, 0.050 mmol) obtained in Example 208 and palladium carbon (10 mg) was stirred under hydrogen atmosphere for 4 hours. After a catalyst was filtered off, the filtrate was concentrated under reduced pressure. The resulting residue was purified by aluminum B column chromatography (development solvent; ethyl acetate), powdered with ethyl acetate-hexane (1:3), to give the titled compound (4.0 mg).

Provenance & Evidence