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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1242980Generated: October 31, 2026

2-Pyrrolidone → HCID 11367213, compound

https://huagongshe.com/reaction/1242980

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyrrolidoneHCID 12025—
Reactant2-BromothiopheneHCID 13851—
ProductHCID 11367213HCID 1136721395%

Reaction Steps

Using general procedure C, 2-bromothiophene was coupled with 2-pyrrolidinone with the reaction time of 16 h. Chromatography gave 158 mg (95%) of the title compound as a solid. 1H NMR (CDCl3, 300 MHz): δ 6.94–6.86 (m, 2H), 6.53 (br s, 1H), 3.89 (t, 2H, J=7.2 Hz), 2.63 (t, 2H, J=8.1 Hz), 2.24 (p, 2H, J=7.5 Hz).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115784B2
Source datasetuspto-grants-2006_10
ORD IDord-e2e142d18b054747aed7a9a77152df64
Source noteuspto-grants-2006_10