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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12430Generated: October 28, 2026

2-(3-phenyl-1H-pyrazol-1-yl)pyridine-3-carboxylic acid → N-{1-[Amino(oxo)acetyl]pentyl}-2-(3-phenyl-1H-pyrazol-1-yl)nicotinamide

https://huagongshe.com/reaction/12430

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-phenyl-1H-pyrazol-1-yl)pyridine-3-carboxylic acidHCID 66719960—
ReactantHCID 73425063HCID 73425063—
ProductN-{1-[Amino(oxo)acetyl]pentyl}-2-(3-phenyl-1H-pyrazol-1-yl)nicotinamideHCID 25157358—

Reaction Steps

Preparation in analogy to Example 5 by coupling 2-(3-phenyl-1H-pyrazol-1-yl)pyridine-3-carboxylic acid and 3-amino-2-hydroxyheptanamide hydrochloride and subsequent oxidation afforded 40 mg of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728012B2
Source datasetuspto-grants-2010_06
ORD IDord-716eb6f2d6eb4ce88d4e17552e7be911
Source noteuspto-grants-2010_06