4-Amino-1-butanol → 4-(N-(3,5-Dimethylphenyl)amino)butanol

Beteiligte Stoffe

Reaktionsschritte

Using the general procedure, 5-bromo-m-xylene (136 μL, 1.0 mmol) was coupled with 4-aminobutanol (138 μL, 1.5 mmol). Purification of the crude product by column chromatography on silica gel using hexane/ethyl acetate (2:1) as eluent afforded the desired product as a colorless oil (174 mg, 90% yield). Rf=0.4 (hexane/ethyl acetate=1:1).

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