2-(1-oxo-3,4,5,6,7,8-hexahydrobenzothieno[2,3-c]pyridin-2(1H)-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl Acetate → {2-[4-Methyl-6-({4-[1-(oxetan-3-yl)piperidin-4-yl]phenyl}amino)-5-oxo-4,5-dihydropyrazin-2-yl]-6-{6-oxo-8-thia-5-azatricyclo[7.4.0.02,7]trideca-1(9),2(7)-dien-5-yl}phenyl}methyl Acetate
Reaction equation
[Br:1][c:2]1[n:3][c:4]([NH:10][c:11]2[cH:12][cH:13][c:14]([CH:17]3[CH2:18][CH2:19][N:20]([CH:23]4[CH2:24][O:25][CH2:26]4)[CH2:21][CH2:22]3)[cH:15][cH:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1.[C:27]([CH3:28])(=[O:29])[O:30][CH2:31][c:32]1[c:33]([N:47]2[C:48](=[O:60])[c:49]3[c:50]([c:53]4[c:54]([s:55]3)[CH2:56][CH2:57][CH2:58][CH2:59]4)[CH2:51][CH2:52]2)[cH:34][cH:35][cH:36][c:37]1[B:38]1[O:39][C:40]([CH3:41])([CH3:42])[C:43]([CH3:44])([CH3:45])[O:46]1>>[c:2]1(-[c:37]2[c:32]([CH2:31][O:30][C:27]([CH3:28])=[O:29])[c:33]([N:47]3[C:48](=[O:60])[c:49]4[c:50]([c:53]5[c:54]([s:55]4)[CH2:56][CH2:57][CH2:58][CH2:59]5)[CH2:51][CH2:52]3)[cH:34][cH:35][cH:36]2)[n:3][c:4]([NH:10][c:11]2[cH:12][cH:13][c:14]([CH:17]3[CH2:18][CH2:19][N:20]([CH:23]4[CH2:24][O:25][CH2:26]4)[CH2:21][CH2:22]3)[cH:15][cH:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b3a8dfb578aa4e9fbb4ac40650031f88
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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